Overview of Chosen Chemical Compounds and Intermediates
Overview of Chosen Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or research is crucial for making certain the purity and basic safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A important compound in the synthesis of imatinib, a drug that targets distinct sorts of cancer, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the manufacturing course of action and ensuring substantial purity.
Lapatinib 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is employed to treat breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Utilized in the therapy of breast cancer. Many intermediates help in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and small cell lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have a variety of applications, including antiviral Qualities.
Vildagliptin Intermediates: Used in the Abiraterone Acetate Intermediate production of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-four to control blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication applied to control variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).